Biopsy Micropipettes

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A comprehensive range for all preferences

CooperSurgical^® biopsy micropipettes offer precision and accuracy during the delicate process of oocyte or/and embryo biopsy. Our micropipettes are specifically designed for assisted reproduction techniques (ART) and provide optimal results for preimplantation genetic testing (PGT). With advanced technology and expert engineering, our micropipettes help to ensure minimal trauma to the embryo and consistent performance.

Explore our range of biopsy micropipettes and discover why CooperSurgical is a trusted name in fertility solutions.

Our range of pipettes designed for biopsies is available in different sizes and design for polar body, blastomere or trophectoderm biopsy procedures.

The combined portfolio of ORIGIO® and The Pipette Company TPC™ micropipettes provides a variety of key features to fit most user preferences, including angle choices, bevel length, inner diameter, and taper. Explore the range and find your perfect fit.

Availability
These products are available for sale in Europe, the USA, Canada and Australia, as well as selected countries in the rest of the world.

ORIGIO^® Micropipettes

Biopsy pipettes to suit every need – polar body, blastomere or trophectoderm biopsy procedures.

Designed to remove polar bodies or blastomeres or trophectoderm cells for genetic analysis
Polar body biopsy micropipette options are: flat/polished, beveled/polished, and beveled/spiked
Blastomere biopsy pipettes come in 5 sizes and are suitable for removing a single blastomere or a group of trophectoderm cells. ID ranging 18-27µm is advised for blastomeres and trophectoderm.

TPC™ Biopsy Micropipettes

The flat or beveled heat-polished tips in these micropipettes help to facilitate the removal of a single blastomere or group of trophectoderm cells.

The long parallel taper of these micropipettes provides smooth effortless fluid control during micromanipulation.¹

Packaging

ORIGIO pipettes packaging

All our ORIGIO micropipettes are packaged in a transparent compact box of 10.

Takes less shelf space
Allows for a very quick overview of how many pipettes are left
Tip protector included in each micropipette tube

Please watch the video if you would like to see how easy it is to take an ORIGIO micropipette out of its packaging.

TPC pipettes packaging

All our TPC micropipettes are packaged in a recyclable cardboard box of 10. CooperSurgical encourages all clinics to recycle when possible.

Pipettes are individually packaged and gamma sterilized for optimum sterility. For easy identification, pipettes are packed in color-coded protective holders. Outer labels are also color-coded.

Choosing the right biopsy micropipette depends on a variety of factors, including the stage at which you are performing biopsy, the size and quality of the embryos, and the preferences of the embryologist or fertility specialist. It is important to work with a trusted supplier of fertility equipment and consult with an expert in the field to determine the best micropipette for your specific needs.

Micropipettes that are designed specifically for assisted reproduction techniques and undergo rigorous quality control measures can help improve the success rates of IVF and other fertility treatments, leading to better outcomes for patients.

The ESHRE PGT Consortium recommends to change the biopsy pipette for each embryo/oocyte to avoid cross-contamination.²

It is the same as for any micropipette used for aspiration, such as ICSI pipettes.

All our pipettes should be stored at room temperature, in the original unopened packaging, away from contamination, moisture and direct heat.

If you would you like to improve your skills, and knowledge about embryo biopsy for PGT, please watch our educational on-demand webinars:

Tubing of Cells for Preimplantation Genetic Testing – Part 1

Tubing of Cells for Preimplantation Genetic Testing – Part 2

All About Lasers in ART

References

Dianna Payne (2010), “Commentary: Oocyte degeneration following ICSI”, Journal of Reproductive and Stem Cell Biotechnology, Vol 1, No 9, page 194
ESHRE PGT Consortium and SIG-Embryology Biopsy Working Group; Kokkali G, Coticchio G, Bronet F, Celebi C, Cimadomo D, Goossens V, Liss J, Nunes S, Sfontouris I, Vermeulen N, Zakharova E, De Rycke M. ESHRE PGT Consortium and SIG Embryology good practice recommendations for polar body and embryo biopsy for PGT. Hum Reprod Open. 2020 May 29;2020(3): hoaa020.DOI: 10.1093/hropen/hoaa020. PMID: 32500104; PMCID: PMC7257009.

Product codes

ORIGIO® Micropipettes

Tip type	Order Code	Bend Angles (XX in ref. no.)	Tip to Bend Distance	Bevel Angle	Inner Diameter (μm)
Flat and Polished	MBB-FP-SM-XX	0°, 20°, 25°, 30°, 35°	0.4mm	–	27.5-32.5
Flat and Polished	MBB-FP-M-XX	0°, 20°, 25°, 30°, 35°	0.4mm	–	32.5-37.5
Flat and Polished	MBB-FP-L-XX	30°, 35°	0.4mm	–	37.5-42.5
Flat and Polished	MBB-FP-XXS-XX	30°, 35°	0.4mm	–	18-22
Flat and Polished	MBB-FP-XS-XX	30°, 35°	0.4mm	–	23-27
Bevelled and Polished	MBB-BP-SM-XX	30°, 35°	0.4mm	45°	27.5-32.5
Bevelled and Polished	MBB-BP-M-XX	30°, 35°	0.4mm	45°	32.5-37.5
Small, Bevelled and Spiked	MPB-BS-XX	30°	0.45mm	45°	14-16
Small, Flat and Polished	MPB-FP-XX	30°	0.45mm	–	13-15

TPC™ Biopsy Micropipettes

Tip Type	Order Code	Bevel Angle	Inner Diameter (µm)	Outer Diameter (µm)	Tip to Bend Distance
Beveled and Polished 40°	LBSR	30°	25-29µm	29-33µm	1mm
Flat and Polished	LBC-OD27BA90	30°	23-27µm	23-27µm	1mm
Flat and Polished	LBC-OD30BA90	30°	25-29µm	25-29µm	1mm
Flat and Polished	LBC-OD32TA35	35°	28-32µm	28-32µm	1mm
Flat and Polished	LBC-OD35BA90	30°	31-35µm	31-35µm	1mm
Flat and Polished	LBC-OD35TA35	35°	31-35µm	31-35µm	1mm
Flat and Polished	LBC-OD40BA90	30°	35-39µm	35-39µm	1mm
Flat and Polished	LBC-OD40TA35	35°	35-39µm	35-39µm	1mm

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Brochures, Catalogs & Flyers

Product Data Sheet

ORIGIO Micropipettes Product Data Sheet

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TPC Micropipettes Product Data Sheet

View PDF

Biopsy pipettes are available depending on personal preference. Flat biopsy pipettes are the most popular for extracting cells.

Smaller biopsy pipettes such as the 14 micron is ideal for this. Usually Polar Body Biopsies are performed with a spiked pipette but if the procedure is laser-assisted then a flat end is equally suitable.

There are a few different techniques and preferences out there. But the good news is, we can supply any type of pipet that matches their preference. Most commonly people will use flat and polished pipettes:
MBB-FP-SM-(angle) – flat & polished, 30µm I.D.
MBB-FP-XS-(angle) – flat & polished, 25µm I.D.
MBB-FP-XXS-(angle) – flat & polished, 20µm I.D.
The important thing to note about the size options for trophectoderm pipette, is that smaller ID pipettes tend to give more fine suction control. This may be beneficial when trying to aspirate as few trophectoderm cells as possible.

Procedures

Embryo Biopsy

The full solution for efficient and effective biopsy procedures

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Biopsy Micropipettes