ZyMōt™ Sperm Separation Device
From
Sperm preparation made easy
ZyMōt™ represents a fundamental change in thinking about how to effectively separate high-quality sperm1 for ART procedures.
The ZyMōt™ Sperm Separation Device is an innovative and simple way2 to isolate high-quality, motile sperm1 for use in ICSI, IVF and IUI procedures, separating sperm with low DNA fragmentation.3
Simple to adopt
Minimal training requirements when using the ZyMōt™ device equate to more flexibility across users with varying levels of experience.4
Easy to use
The ZyMōt™device is simple to use,4 helping labs quickly achieve high-quality sperm separation for ART procedures.1
Saves time
The ZyMōt™ Sperm Separation Device equates to hands-on time savings5 and workflow standardization.4
Reduces lab risks
ZyMōt™ requires fewer handling steps per sample,4 which could help reduce the risk of errors.2
Proven success6
One sperm and one egg are all that is needed to begin the process of creating an embryo. ZyMōt™ provides high-quality sperm3 for ART procedures, which can increase the odds of a successful fertility treatment cycle.7
For men with high sperm DNA fragmentation, ZyMōt-processed samples has been shown to enhance fertilization, embryo development, and clinical pregnancy rates.8
How it works
- Liquefied semen is placed into a lower chamber and fresh medium in an upper chamber, separated by a permeable polycarbonate membrane with 8µm pores
- Motile sperm can swim through the pores and are harvested from the upper chamber
- Sperm accumulate at boundaries with a changed swimming pattern (flattened slither) within 1µm that is 50% faster.9
Simplifying and standardizing workflow
The ZyMōt™ device simplifies and standardizes workflow in the lab, for ICSI, IVF and IUI.4
ZyMōt™ Sperm Separation Steps
To learn more about how the ZyMōt™ sperm separation device can help you effectively separate high-quality sperm, contact your local CooperSurgical representative.
Product codes
| Order Code | Product Name | Processing Volume (mL) | Pack Size |
|---|---|---|---|
| ZMH0850 | ZyMōt™ Multi 850μL Sperm Separation Device | 850μL | 10 units per pack |
| ZMH3000 | ZyMōt™ Multi 3mL Sperm Separation Device | 3mL | 10 units per pack |
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Brochures, Catalogs & Flyers
Product Data Sheet
Product Data Sheet
- Broussard, A., et al. Sperm DNA Fragmentation (SDF) was most effectively Improved by a sperm separation device Compared to Different Gradient and Swim up Methods. Fertil Steril. 2019, 111(4);e15
- Ogbejesi C., et al. MICROFLUIDIC SPERM SORTING COMPARED WITH TRADITIONAL DENSITY GRADIENT CENTRIFUGATION: A COST ANALYSIS. Fertil Steril. 2022, 118(4); e142
- Bastuba M., et al. MICROFLUIDIC SPERM SEPARATION DEVICE DRAMATICALLY LOWERS DFI. Fertil Steril. 2020, 113(4); e44
- Asghar W., et al. Selection of functional human sperm with higher DNA integrity and fewer reactive oxygen species. Adv Healthc Mater. 2014 Oct;3(10):1671-9
- Adolfsson, E., et al. Clinical Validation and Experiences of the Microfluidics Sperm Preparation Device ZyMōt™. RBMO Alpha Conference
- Gode F., et al. Comparison of microfluid sperm sorting chip and density gradient methods for use in intrauterine insemination cycles. Fertil Steril. 2019. 112(5); 842-848
- Banti, M., Van Zyl, E., Kafetzis, D. (2024). Sperm Preparation with Microfluidic Sperm Sorting Chip May Improve Intracytoplasmic Sperm Injection Outcomes Compared to Density Gradient Centrifugation. Reproductive sciences. doi:https://doi.org/10.1007/s43032-024-01483-1.
- Kocur, O., et al. Can a sperm selection technique improve embryo ploidy? Andrology, 2023 November; 11(8): 1605-1612.
- Nosrati, R., et al. 2017. Microfluidics for sperm analysis and selection. Nature Reviews Urology, 14(12), pp.707–720.
Procedures
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Service
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